Skip to main content
October 1, 2019

JACC: BTS | Vol. 4 No. 6

CLINICAL RESEARCH

First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients

First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients

Clinical Research
  • Jay H. Traverse,
  • Karen L. Christman,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 659–669.

PRECLINICAL RESEARCH

Quantification of DNA Damage in Heart Tissue as a Novel Prediction Tool for Therapeutic Prognosis of Patients With Dilated Cardiomyopathy

Quantification of DNA Damage in Heart Tissue as a Novel Prediction Tool for Therapeutic Prognosis of Patients With Dilated Cardiomyopathy

Preclinical Research
  • Toshiyuki Ko,
  • Issei Komuro,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 670–680.

DNA Damage Prediction Tool in Dilated Cardiomyopathy: Don’t Go Breaking My Heart

Editorial Comment
  • Jesus Jimenez and
  • Stacey L. Rentschler

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 681–683.

JAK2V617F-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure

JAK2V617F-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure

Preclinical Research
  • Soichi Sano,
  • Kenneth Walsh,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 684–697.

A New Murine Model of Clonal Hematopoiesis Investigates JAK2V617F in Heart Failure

Editorial Comment
  • Aniruddh P. Patel and
  • Pradeep Natarajan

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 698–700.

Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction

Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction

Preclinical Research
  • Yuya Ide,
  • Koh Ono,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 701–714.

The Art of War in Drug Development

Editorial Comment
  • Taro Kariya and
  • Kiyotake Ishikawa

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 715–716.

Acute Kidney Injury Induces Remote Cardiac Damage and Dysfunction Through the Galectin-3 Pathway

Acute Kidney Injury Induces Remote Cardiac Damage and Dysfunction Through the Galectin-3 Pathway

Preclinical Research
  • Mathilde Prud’homme,
  • Matthieu Legrand,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 717–732.

The Kidney, Bone Marrow, and Heart Connection in Acute Kidney Injury: Role of Galecin-3

Editorial Comment
  • Yang Chen and
  • John C. Burnett

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 733–735.

TRANSLATIONAL MODEL

A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target

A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target

Translational Model
  • Jonathan D. Moreno,
  • Jonathan R. Silva,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 736–751.

How to Boost Efficacy of a Sodium Channel Blocker: The Devil Is in the Details

Editorial Comment
  • Madison B. Nowak,
  • Seth H. Weinberg,
  • et. al.

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 752–754.

STATE-OF-THE-ART REVIEW

Angiopoietin-Like 3: From Discovery to Therapeutic Gene Editing

Angiopoietin-Like 3: From Discovery to Therapeutic Gene Editing

State-of-the-art Review
  • Xiao Wang and
  • Kiran Musunuru

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) 755–762.

Full Issue PDF

J Am Coll Cardiol Basic Trans Science. 2019 Oct, 4 (6) I–CVII.